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Product Info Summary
| SKU: | A02659 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-PDE6B Antibody
SKU/Catalog Number
A02659
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PDE6B Antibody catalog # A02659. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PDE6B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02659)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human TASK-1 at amino acid range 47-96
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02659 is reactive to PDE6B in Human, Mouse, Rat
Applications
A02659 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
98.336kDa
Background of PDE6 beta
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Ota T., Nat. Genet. 36:40-45(2004).
Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).
Brill L.M., Anal. Chem. 76:2763-2772(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-PDE6B Antibody A02659
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For PDE6B (Source: Uniprot.org, NCBI)
Gene Name
PDE6B
Full Name
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Weight
98.336kDa
Superfamily
cyclic nucleotide phosphodiesterase family
Alternative Names
CSNB3; EC 3.1.4; EC 3.1.4.35; GMP-PDE beta; PDEBrod cGMP-phosphodiesterase beta-subunit; phosphodiesterase 6B, cGMP-specific, rod, beta; rd1; rod cGMP-specific 3'-5'-cyclic phosphodiesterase subunit beta; RP40CSNBAD2 PDE6B CSNB3, CSNBAD2, GMP-PDEbeta, PDEB, RP40, rd1 phosphodiesterase 6B rod cGMP-specific 3,5-cyclic phosphodiesterase subunit beta|GMP-PDE beta|phosphodiesterase 6B, cGMP-specific, rod, beta|rod cGMP-phosphodiesterase beta-subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PDE6B, check out the PDE6B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PDE6B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PDE6B Antibody (A02659)
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No publications found for A02659
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Customer Reviews
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