Product Info Summary
SKU: | A01075S662 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-Per2 (S662) Antibody
SKU/Catalog Number
A01075S662
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-Per2 (S662) Antibody catalog # A01075S662. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-Per2 (S662) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01075S662)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Per2 around the phosphorylation site of S662.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01075S662 is reactive to PER2 in Human, Mouse
Applications
A01075S662 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
136.579kDa
Background of PER2
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of PER2 using Anti-Phospho-Per2 (S662) Antibody (A01075S662).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°CClick image to see more details
Figure 1. Western blotting validation for Anti-Phospho-Per2 (S662) Antibody A01075S662
Western Blot (WB) analysis of 3T3 cells using Phospho-Per2 (S662) polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For PER2 (Source: Uniprot.org, NCBI)
Gene Name
PER2
Full Name
Period circadian protein homolog 2
Weight
136.579kDa
Alternative Names
Circadian clock protein PERIOD 2; FASPS; hPER2; KIAA0347period 2; period (Drosophila) homolog 2; period circadian protein 2; period circadian protein homolog 2; period homolog 2 (Drosophila) PER2 FASPS, FASPS1 period circadian regulator 2 period circadian protein homolog 2|circadian clock protein PERIOD 2|hPER2|period 2|period circadian clock 2|period circadian protein 2|period homolog 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PER2, check out the PER2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PER2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Per2 (S662) Antibody (A01075S662)
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No publications found for A01075S662
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