Product Info Summary
SKU: | A02516S311 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-SPAK (S311) STK39 Antibody
SKU/Catalog Number
A02516S311
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-SPAK (S311) STK39 Antibody catalog # A02516S311. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-SPAK (S311) STK39 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02516S311)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SPAK around the phosphorylation site of S311.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02516S311 is reactive to STK39 in Human, Mouse, Rat
Applications
A02516S311 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
59.474kDa
Background of STK39
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry analysis of paraffin-embedded human brain, using STK39 (Phospho-Ser311) Antibody. The picture on the right is blocked with the phospho peptide.
Protein Target Info & Infographic
Gene/Protein Information For STK39 (Source: Uniprot.org, NCBI)
Gene Name
STK39
Full Name
STE20/SPS1-related proline-alanine-rich protein kinase
Weight
59.474kDa
Superfamily
protein kinase superfamily
Alternative Names
DCHTsmall intestine SPAK-like kinase; DKFZp686K05124; EC 2.7.11; EC 2.7.11.1; PASK; proline-alanine-rich STE20-related kinase; serine threonine kinase 39; Serine/threonine-protein kinase 39; SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast); STE20/SPS1 homolog; STE20/SPS1-related proline-alanine-rich protein kinase; Ste20-like protein kinase; Ste-20-related kinase STK39 DCHT, PASK, SPAK serine/threonine kinase 39 STE20/SPS1-related proline-alanine-rich protein kinase|STE20/SPS1 homolog|Ste20-like protein kinase|proline-alanine-rich STE20-related kinase|serine threonine kinase 39 (STE20/SPS1 homolog, yeast)|serine/threonine-protein kinase 39|small intestine SPAK-like kinase|ste-20-related kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STK39, check out the STK39 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STK39: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-SPAK (S311) STK39 Antibody (A02516S311)
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No publications found for A02516S311
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Customer Reviews
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