Product Info Summary
SKU: | A06738-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Phospholipase A2 PLA2G1B Antibody
SKU/Catalog Number
A06738-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospholipase A2 PLA2G1B Antibody catalog # A06738-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospholipase A2 PLA2G1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06738-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human MBTPS1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06738-1 is reactive to PLA2G1B in Human, Mouse
Applications
A06738-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
16.36kDa
Background of PLA2G1B
Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.
Nakajima T., J. Hum. Genet. 45:212-217(2000).
Nagase T., DNA Res. 2:37-43(1995).
Bechtel S., BMC Genomics 8:399-399(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:100-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Phospholipase A2 PLA2G1B Antibody A06738-1
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For PLA2G1B (Source: Uniprot.org, NCBI)
Gene Name
PLA2G1B
Full Name
Phospholipase A2
Weight
16.36kDa
Superfamily
phospholipase A2 family
Alternative Names
Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2; phospholipase A2, group IB (pancreas); PLA2; PLA2A; PLA2AMGC119834; PLA2EC 3.1.1.4; PLA2G1B; PPLA2; PPLA2MGC119835 PLA2G1B PLA2, PLA2A, PPLA2 phospholipase A2 group IB phospholipase A2|phosphatidylcholine 2-acylhydrolase 1B|phospholipase A2, group IB (pancreas)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PLA2G1B, check out the PLA2G1B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PLA2G1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospholipase A2 PLA2G1B Antibody (A06738-1)
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No publications found for A06738-1
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