Product Info Summary
SKU: | A05366-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-PKA Beta cat PRKACB Antibody
View all PKA C beta Antibodies
SKU/Catalog Number
A05366-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PKA Beta cat PRKACB Antibody catalog # A05366-1. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PKA Beta cat PRKACB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05366-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human KAPCB.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05366-1 is reactive to PRKACB in Human, Mouse, Rat
Applications
A05366-1 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
40.623kDa
Background of PKA C beta
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For PRKACB (Source: Uniprot.org, NCBI)
Gene Name
PRKACB
Full Name
cAMP-dependent protein kinase catalytic subunit beta
Weight
40.623kDa
Superfamily
protein kinase superfamily
Alternative Names
cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit beta; cAPKbeta; DKFZp781I2452; EC 2.7.11; EC 2.7.11.11; MGC41879; MGC9320; PKA C beta; PKA C-beta; PKACB; PRKACB; protein kinase A catalytic subunit beta; protein kinase, cAMP-dependent, catalytic, beta PRKACB CAFD2, PKA C-beta, PKACB protein kinase cAMP-activated catalytic subunit beta cAMP-dependent protein kinase catalytic subunit beta|protein kinase A catalytic subunit beta|protein kinase, cAMP-dependent, beta catalytic subunit|protein kinase, cAMP-dependent, catalytic, beta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRKACB, check out the PRKACB Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRKACB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PKA Beta cat PRKACB Antibody (A05366-1)
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No publications found for A05366-1
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-PKA Beta cat PRKACB Antibody
Question
Does A05366-1 contain the amino acid D324?
Verified customer
Asked: 2021-01-27
Answer
Yes, the Anti-PKA Beta Cat PRKACB Antibody (A05366-1) contains the amino acid D324.
Boster Scientific Support
Answered: 2021-01-28