Product Info Summary
SKU: | A06773 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-PLOD3 Antibody
SKU/Catalog Number
A06773
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PLOD3 Antibody catalog # A06773. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PLOD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06773)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human MLF1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06773 is reactive to PLOD3 in Human, Mouse, Rat
Applications
A06773 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
84.785kDa
Background of PLOD3
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204].
Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101].
Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-PLOD3 Antibody A06773
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For PLOD3 (Source: Uniprot.org, NCBI)
Gene Name
PLOD3
Full Name
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
Weight
84.785kDa
Alternative Names
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 PLOD3 LH3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3|lysine hydroxylase 3|lysyl hydroxlase 3|lysyl hydroxylase 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PLOD3, check out the PLOD3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PLOD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PLOD3 Antibody (A06773)
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No publications found for A06773
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Customer Reviews
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