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Product Info Summary
| SKU: | A14868 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-PPAPDC2 PLPP6 Antibody
View all PDP1/PPAPDC2 Antibodies
SKU/Catalog Number
A14868
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PPAPDC2 PLPP6 Antibody (Catalog # A14868). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PPAPDC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PPAPDC2 PLPP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14868)
Host
Rabbit
Contents
PPAPDC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
PPAPDC2 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus human PPAPDC2. The immunogen is located within amino acids 170 - 220 of PPAPDC2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of SPATA6 are known to exist; this antibody will detect only the longest two isoforms. SPATA6 antibody is predicted to not cross-react with other SPATA protein family members.
Reactive Species
A14868 is reactive to PLPP6 in Human, Mouse, Rat
Applications
A14868 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
32.194kDa
Background of PDP1/PPAPDC2
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PPAPDC2 antibody can be used for detection of PPAPDC2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of PPAPDC2 in Raji cells with PPAPDC2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PLPP6 (Source: Uniprot.org, NCBI)
Gene Name
PLPP6
Full Name
Phospholipid phosphatase 6
Weight
32.194kDa
Superfamily
PA-phosphatase related phosphoesterase family
Alternative Names
bA6J24.6; EC 3.1.3; EC 3.1.3.-; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; Phosphatidic acid phosphatase type 2 domain-containing protein 2; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; presqualene diphosphate phosphatase; PSDP PLPP6 PDP1, PPAPDC2, PSDP, bA6J24.6 phospholipid phosphatase 6 phospholipid phosphatase 6|PPAP2 domain-containing protein 2|phosphatidic acid phosphatase type 2 domain containing 2|phosphatidic acid phosphatase type 2 domain-containing protein 2|polyisoprenoid diphosphate phosphatase type 1|presqualene diphosphate phosphatase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PLPP6, check out the PLPP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PLPP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PPAPDC2 PLPP6 Antibody (A14868)
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No publications found for A14868
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Customer Reviews
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