Product Info Summary
SKU: | M03863 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | ELISA, WB |
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Product info
Product Name
Anti-PR3 PRTN3 Monoclonal Antibody
View all Proteinase 3/Myeloblastin/PRTN3 Antibodies
SKU/Catalog Number
M03863
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PR3 PRTN3 Monoclonal Antibody catalog # M03863. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PR3 PRTN3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03863)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
3B4
Isotype
IgG
Immunogen
Purified recombinant fragment of human PR3 expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M03863 is reactive to PRTN3 in Human
Applications
M03863 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
27.807kDa
Background of Proteinase 3/Myeloblastin/PRTN3
Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis using PR3 Monoclonal Antibody against PRTN3 (aa28-256)-hIgGFc transfected HEK293 cell lysate (1).
Protein Target Info & Infographic
Gene/Protein Information For PRTN3 (Source: Uniprot.org, NCBI)
Gene Name
PRTN3
Full Name
Myeloblastin
Weight
27.807kDa
Superfamily
peptidase S1 family
Alternative Names
ACPA; AGP7; AGP7PR3; azurophil granule protein 7; C-ANCA; EC 3.4.21; EC 3.4.21.76; Leukocyte proteinase 3; MBN; MBT; Myeloblastin; Neutrophil proteinase 4; NP4; NP-4; P29C-ANCA antigen; PR-3CANCA; Proteinase 3; PRTN3; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen PRTN3 ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3 proteinase 3 myeloblastin|C-ANCA antigen|Wegener granulomatosis autoantigen|azurophil granule protein 7|leukocyte proteinase 3|neutrophil proteinase 4|serine proteinase, neutrophil|wegener autoantigen
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRTN3, check out the PRTN3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRTN3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PR3 PRTN3 Monoclonal Antibody (M03863)
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No publications found for M03863
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