Product Info Summary
SKU: | A03628 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Protein ERGIC-53 LMAN1 Antibody
SKU/Catalog Number
A03628
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Protein ERGIC-53 LMAN1 Antibody catalog # A03628. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Protein ERGIC-53 LMAN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03628)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GPR55 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03628 is reactive to LMAN1 in Human, Mouse, Rat
Applications
A03628 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.549kDa
Background of LMAN1
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For LMAN1 (Source: Uniprot.org, NCBI)
Gene Name
LMAN1
Full Name
Protein ERGIC-53
Weight
57.549kDa
Alternative Names
ERGIC-53; ERGIC53ER-Golgi intermediate compartment 53 kDa protein; F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53; FMFD1; Gp58; intracellular mannose specific lectin; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose-binding, 1; MCFD1coagulation factor V-factor VIII combined deficiency; MR60; protein ERGIC-53 LMAN1 ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58 lectin, mannose binding 1 protein ERGIC-53|ER-Golgi intermediate compartment 53 kDa protein|endoplasmic reticulum-golgi intermediate compartment protein 53|intracellular mannose-specific lectin MR60
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LMAN1, check out the LMAN1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LMAN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein ERGIC-53 LMAN1 Antibody (A03628)
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No publications found for A03628
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