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- Table of Contents
Protein ERGIC-53 Antibodies
AND LMAN1 ELISA kits, Protein ERGIC-53 Proteins
Many biological assays use antibodies to detect Protein ERGIC-53, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein ERGIC-53 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein ERGIC-53 antibodies...
Designing a Western blot for Protein ERGIC-53? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LMAN1 Western Blot GuideLMAN1 Infographic by Boster Bio
All LMAN1 Products
Product
Figures
Specificity
Applications
Price
Anti-MT-CO2 Antibody Picoband®
4 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03631-1
100 μg/vial
Cat # A03631-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A03628-1
100 μg/vial
Cat # A03628-1
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03637-1
100 μg/vial
Cat # A03637-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M03628-3
100 μl/vial
Cat # M03628-3
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03635-1
100 μg/vial
Cat # A03635-1
100 μg/vial
Dog, Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03628
100 µl
Cat # M03628
100 µl
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03628-2
100 µl
Cat # M03628-2
100 µl
LMAN1 Overview
Facts about Protein ERGIC-53.
Protein ERGIC-53 (LMAN1)
Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.
The LMAN1-MCFD2 complex forms a specific cargo receptor to the ER-to-Golgi transport of selected proteins. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LMAN1 |
| Uniprot: | P49257 |
| Entrez: | 3998 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ERGIC-53; ERGIC53ER-Golgi intermediate compartment 53 kDa protein; F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53; FMFD1; Gp58; intracellular mannose specific lectin; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose-binding, 1; MCFD1coagulation factor V-factor VIII combined deficiency; MR60; protein ERGIC-53
Molecular Weight
Mass (kDA):
57.549 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q21.32 |
| Sequence: | 18; NC_000018.10 (59327823..59359265, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Diseases
- Factor V Deficiency
- Hemophilia A
- Hemorrhage
- Bleeding Tendency
- Familial Multiple Factor Deficiency Syndrome, Type I
- Blood Coagulation Disorders
- Coagulation Factor Deficiency
- Vesicular Stomatitis
- Stomatitis
- Blood Coagulation Disorders, Inherited
- Hemorrhagic Disorders
- Spots On Skin
Interacting Proteins
- ERP44
- MCFD2
- SURF4
Pathways
- Transport
- Secretory Pathway
- Coagulation
- Localization
- Secretion
- Glycosylation
- Intracellular Transport
- Protein Transport
- Blood Coagulation
- Translation
- Mitosis
- Rna Interference
- Microtubule Depolymerization
PTMs
- Glycosylation
- Phosphorylation
- Biotinylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMAN1
bosterbio.com/bosterbio-gene-info-cards/LMAN1
References
PMID: 8223692 by Schindler R., et al. ERGIC-53, a membrane protein of the ER-Golgi intermediate compartment, carries an ER retention motif.
PMID: 7876089 by Arar C., et al. ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.