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Product Info Summary
| SKU: | M01985-2 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-PROX1 Antibody (Center)
SKU/Catalog Number
M01985-2
Size
80 µl
Description
Boster Bio Anti-PROX1 Antibody (Center) (Catalog # M01985-2). Tested in WB application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-PROX1 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01985-2)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This PROX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 444-478 amino acids from the Central region of human PROX1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01985-2 is reactive to PROX1 in Human, Mouse
Applications
M01985-2 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
83.203kDa
Background of PROX1
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-PROX1 Antibody (Center) at 1:1000 dilution
Lane 1: human heart lysates
Lane 2: mouse brain lysates
Lane 3: HepG2 whole cell lysates
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 83 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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Anti-PROX1 Antibody (Center) at 1:2000 dilution + SH-SY5Y whole cell lysates
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 83 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For PROX1 (Source: Uniprot.org, NCBI)
Gene Name
PROX1
Full Name
Prospero homeobox protein 1
Weight
83.203kDa
Superfamily
Prospero homeodomain family
Alternative Names
Homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox1; PROX-1 PROX1 prospero homeobox 1 prospero homeobox protein 1|homeobox prospero-like protein PROX1|prospero-related homeobox 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PROX1, check out the PROX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PROX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PROX1 Antibody (Center) (M01985-2)
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No publications found for M01985-2
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Customer Reviews
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