Anti-PSR JMJD6 Monoclonal Antibody

Product Name

Anti-PSR JMJD6 Monoclonal Antibody

View all JMJD6/PSR Antibodies

SKU/Catalog Number

A03690

Size

100μl

Form

Liquid

Description

Boster Bio Anti-PSR JMJD6 Monoclonal Antibody catalog # A03690. Tested in IF, IHC, WB applications. This antibody reacts with Bovine, Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PSR JMJD6 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03690)

Host

Mouse

Contents

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Clonality

Monoclonal

Clone Number

5A6

Isotype

IgG

Immunogen

Purified recombinant human PSR (N-terminal) protein fragments expressed in E.coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03690 is reactive to JMJD6 in Bovine, Human, Mouse, Rat

Applications

A03690 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

46.462kDa

Background of JMJD6/PSR

CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:1000-1:2000
IF, 1:100-1:500

Validation Images & Assay Conditions

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Western Blot (WB) analysis using PSR Monoclonal antibody against HeLa, HL-60 cell lysate.

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Immunofluorescence (IF) analysis of HeLa cells using PSR Monoclonal antibody.

Gene/Protein Information For JMJD6 (Source: Uniprot.org, NCBI)

Alternative Names

bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; EC 1.14.11; EC 1.14.11.-; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; JMJD6; jumonji domain containing 6; Jumonji domain-containing protein 6; KIAA0585PSR; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptorPTDSR; Protein PTDSR; PSR; PTDSR; PTDSR1 JMJD6 PSR, PTDSR, PTDSR1 jumonji domain containing 6, arginine demethylase and lysine hydroxylase bifunctional arginine demethylase and lysyl-hydroxylase JMJD6|arginine demethylase and lysine hydroxylase|histone arginine demethylase JMJD6|jmjC domain-containing protein 6|jumonji domain-containing protein 6|lysyl-hydroxylase JMJD6|peptide-lysine 5-dioxygenase JMJD6|phosphatidylserine receptor

For more info on JMJD6, check out the JMJD6 Infographic

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In this infographic, you will see the following information for JMJD6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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