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Product Info Summary
| SKU: | A02957-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-PTK7 Antibody
SKU/Catalog Number
A02957-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PTK7 Antibody (Catalog # A02957-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PTK7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-PTK7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02957-1)
Host
Rabbit
Contents
PTK7 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PTK7 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human PTK7. The immunogen is located within amino acids 880 - 930 of PTK7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.
Reactive Species
A02957-1 is reactive to PTK7 in Human, Mouse, Rat
Applications
A02957-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
118.392kDa
Background of PTK7/CCK4
Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PTK7 antibody can be used for detection of PTK7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human, mouse, and rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PTK7 in (A) human colon
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Immunohistochemistry of PTK7 in human colon tissue with PTK7 antibody at 2.5 μg/mL.
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Immunofluorescence of PTK7 in Human Colon cells with PTK7 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PTK7 (Source: Uniprot.org, NCBI)
Gene Name
PTK7
Full Name
Inactive tyrosine-protein kinase 7
Weight
118.392kDa
Superfamily
protein kinase superfamily
Alternative Names
CCK4; CCK-4; CCK4Colon carcinoma kinase 4; colon carcinoma kinase-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; PTK7; Tyrosine-protein kinase-like 7 PTK7 CCK-4, CCK4 protein tyrosine kinase 7 (inactive) inactive tyrosine-protein kinase 7|PTK7 protein tyrosine kinase 7|colon carcinoma kinase 4|pseudo tyrosine kinase receptor 7|tyrosine-protein kinase-like 7
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTK7, check out the PTK7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTK7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PTK7 Antibody (A02957-1)
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No publications found for A02957-1
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