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Product Info Summary
| SKU: | A06517 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, WB |
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Product info
Product Name
Anti-QPCT Antibody
View all Glutaminyl-peptide Cyclotransferase/QPCT Antibodies
SKU/Catalog Number
A06517
Size
100ul
Form
Liquid
Description
Boster Bio Anti-QPCT Antibody catalog # A06517. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-QPCT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06517)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BCL2L12
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A06517 is reactive to QPCT in Human, Mouse, Rat
Applications
A06517 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
40.877kDa
Background of Glutaminyl-peptide Cyclotransferase/QPCT
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IF: 1:50-1:200
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For QPCT (Source: Uniprot.org, NCBI)
Gene Name
QPCT
Full Name
Glutaminyl-peptide cyclotransferase
Weight
40.877kDa
Superfamily
glutaminyl-peptide cyclotransferase family
Alternative Names
EC 2.3.2.5; GCT; Glutaminyl cyclase; glutaminyl-peptide cyclotransferase; Glutaminyl-tRNA cyclotransferase; Glutamyl cyclase; QCEC; QPCT; sQC QPCT GCT, QC, sQC glutaminyl-peptide cyclotransferase glutaminyl-peptide cyclotransferase|EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on QPCT, check out the QPCT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for QPCT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-QPCT Antibody (A06517)
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No publications found for A06517
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