Product Info Summary
SKU: | A05387-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-R-spondin-3 RSPO3 Antibody
View all R-Spondin 3 Antibodies
SKU/Catalog Number
A05387-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-R-spondin-3 RSPO3 Antibody catalog # A05387-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-R-spondin-3 RSPO3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05387-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human AHNK protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05387-1 is reactive to Rspo3 in Human, Mouse, Rat
Applications
A05387-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
31.454kDa
Background of R-Spondin 3
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Rspo3 (Source: Uniprot.org, NCBI)
Gene Name
Rspo3
Full Name
R-spondin-3
Weight
31.454kDa
Superfamily
R-spondin family
Alternative Names
Cristin 1; CRISTIN1; FLJ14440; hPWTSR; hRspo3; Protein with TSP type-1 repeat; PWTSR; Roof plate-specific spondin-3; RSPO3; R-spondin 3 homolog (Xenopus laevis); RSpondin 3; R-Spondin 3; R-spondin-3; Thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; THSD2 Rspo3|2810459H04Rik, AW742308, Cri, Cristin1, Thsd, Thsd2|R-spondin 3|R-spondin-3|R-spondin 3 homolog|cabriolet|cristin 1|cysteine-rich and single thrombospondin domain-containing protein 1|nucleopondin|roof plate-specific spondin-3|thrombospondin, type I, domain 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Rspo3, check out the Rspo3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Rspo3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-R-spondin-3 RSPO3 Antibody (A05387-1)
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No publications found for A05387-1
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