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Product Info Summary
| SKU: | A03937 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-RABEX5 RABGEF1 Antibody
SKU/Catalog Number
A03937
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-RABEX5 RABGEF1 Antibody (Catalog # A03937). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
RABEX5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-RABEX5 RABGEF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03937)
Host
Rabbit
Contents
RABEX5 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RABEX5 antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5. The immunogen is located within amino acids 430 - 480 of RABEX5.
Cross-reactivity
At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
Reactive Species
A03937 is reactive to RABGEF1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
56.9 kDa
Background of RABGEF1
RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03937 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RABEX5 antibody can be used for detection of RABEX5 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RABEX5 in human liver tissue lysate with RABEX5 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of RABEX5 in mouse brain tissue with RABEX5 antibody at 5 μg/mL.
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Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 μg/mL.
Specific Publications For Anti-RABEX5 RABGEF1 Antibody (A03937)
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