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Product Info Summary
| SKU: | A10682 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody
View all NgR2/NgRH1/RTN4RL2 Antibodies
SKU/Catalog Number
A10682
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody (Catalog # A10682). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
RTN4RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10682)
Host
Rabbit
Contents
RTN4RL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2. The immunogen is located within amino acids 330 - 380 of RTN4RL2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.
Reactive Species
A10682 is reactive to Rtn4rl2 in Human
Applications
A10682 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
46.075kDa
Background of NgR2/NgRH1/RTN4RL2
Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RTN4RL2 in rat brain tissue lysate with RTN4RL2 antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Rtn4rl2 (Source: Uniprot.org, NCBI)
Gene Name
Rtn4rl2
Full Name
Reticulon-4 receptor-like 2
Weight
46.075kDa
Superfamily
Nogo receptor family
Alternative Names
NgR2; NgRH1; reticulon 4 receptor-like 2; RTN4RL2 Rtn4rl2|Ng, Ngr, Ngr2, Ngrh1, Ngrl3|reticulon 4 receptor-like 2|reticulon-4 receptor-like 2|nogo receptor-like 3|nogo-66 receptor homolog 1|nogo-66 receptor-related protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Rtn4rl2, check out the Rtn4rl2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Rtn4rl2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody (A10682)
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