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Product Info Summary
| SKU: | A10435 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-RKHD3 MEX3B Antibody
SKU/Catalog Number
A10435
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-RKHD3 MEX3B Antibody (Catalog # A10435). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
RKHD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-RKHD3 MEX3B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10435)
Host
Rabbit
Contents
RKHD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
RKHD3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RKHD3. The immunogen is located within amino acids 180 - 230 of RKHD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is specific for RKHD3 and will not recognize the other RKHD3 family of proteins.
Reactive Species
A10435 is reactive to MEX3B in Human, Mouse, Rat
Applications
A10435 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
58.832kDa
Background of RKHD3
Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RKHD3 antibody can be used for detection of EPAC1 by Western blot at 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RKHD3 in human testis tissue lysate with RKHD3 antibody at 1 μg/mL.
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Immunofluorescence of RKHD3 in mouse skeletal muscle cells with RKHD3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MEX3B (Source: Uniprot.org, NCBI)
Gene Name
MEX3B
Full Name
RNA-binding protein MEX3B
Weight
58.832kDa
Alternative Names
DKFZp434J0617; KIAA2009; mex-3 homolog B (C. elegans); ring finger and KH domain containing 3; RING finger and KH domain-containing protein 3; RING finger protein 195; RKHD3MGC117199; RNA-binding protein MEX3B; RNF195MEX-3B MEX3B MEX-3B, RKHD3, RNF195 mex-3 RNA binding family member B RNA-binding protein MEX3B|RING finger protein 195|ring finger and KH domain containing 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MEX3B, check out the MEX3B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MEX3B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RKHD3 MEX3B Antibody (A10435)
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No publications found for A10435
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