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Product Info Summary
| SKU: | A00444-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-ROR Gamma RORC Antibody
SKU/Catalog Number
A00444-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ROR Gamma RORC Antibody catalog # A00444-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ROR Gamma RORC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00444-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide, corresponding to amino acids 246-297 of Human RUNX-2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00444-1 is reactive to RORC in Human, Mouse, Rat
Applications
A00444-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
58.195kDa
Background of RORC
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-ROR Gamma RORC Antibody A00444-1
Western blot (WB) analysis of RORγ polyclonal antibody at 1:500 dilutionLane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For RORC (Source: Uniprot.org, NCBI)
Gene Name
RORC
Full Name
Nuclear receptor ROR-gamma
Weight
58.195kDa
Superfamily
nuclear hormone receptor family
Alternative Names
ROR gamma; MGC129539; NR1F3; Nuclear receptor ROR gamma; Nuclear receptor ROR-gamma; Nuclear receptor RZR gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR-Related Orphan Nuclear Receptor Variant 2; RAR-related orphan receptor C; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; Retinoid-related orphan receptor-gamma; ROR gamma; RORC; RORG; RORGMGC129539; RZRG; RZRGRZR-GAMMA; TOR RORC IMD42, NR1F3, RORG, RZR-GAMMA, RZRG, TOR RAR related orphan receptor C nuclear receptor ROR-gamma|RAR-related orphan nuclear receptor variant 2|nuclear receptor RZR-gamma|nuclear receptor subfamily 1 group F member 3|retinoic acid-binding receptor gamma|retinoid-related orphan receptor gamma
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RORC, check out the RORC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RORC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ROR Gamma RORC Antibody (A00444-1)
Hello CJ!
A00444-1 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Li, X.M., Chen, X., Gu, W., Guo, Y.J., Cheng, Y., Peng, J., & Guo, X.J. (2017). Impaired TNF/TNFR2 signaling enhances Th2 and Th17 polarization and aggravates allergic airway inflammation. American Journal of Physiology - Lung Cellular and Molecul...
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