Anti-SECISBP2 Antibody

SECISBP2 antibody

Boster Bio Anti-SECISBP2 Antibody catalog # A06543. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A06543
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, ICC, WB

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Product Name

Anti-SECISBP2 Antibody

View all SECISBP2 Antibodies

SKU/Catalog Number

A06543

Size

100ul

Form

Liquid

Description

Boster Bio Anti-SECISBP2 Antibody catalog # A06543. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SECISBP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06543)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human AMID

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06543 is reactive to SECISBP2 in Human, Mouse, Rat

Applications

A06543 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

95.462kDa

Background of SECISBP2

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Marino G., J. Biol. Chem. 278:3671-3678(2003).
Kabeya Y., J. Cell Sci. 117:2805-2812(2004).
Ross M.T., Nature 434:325-337(2005

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:100

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For SECISBP2 (Source: Uniprot.org, NCBI)

Gene Name

SECISBP2

Full Name

Selenocysteine insertion sequence-binding protein 2

Weight

95.462kDa

Alternative Names

DKFZp686C09169; SBP2SECIS-binding protein 2; SECIS binding protein 2; selenocysteine insertion sequence binding protein 2; selenocysteine insertion sequence-binding protein 2 SECISBP2 SBP2 SECIS binding protein 2 selenocysteine insertion sequence-binding protein 2|Sec insertion sequence-binding protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SECISBP2, check out the SECISBP2 Infographic

SECISBP2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SECISBP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A06543-100ul

100ul

$405

Free Secondary Antibody

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A06543
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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