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Product Info Summary
| SKU: | A00416 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Sepiapterin reductase SPR Antibody
SKU/Catalog Number
A00416
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Sepiapterin reductase SPR Antibody catalog # A00416. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Sepiapterin reductase SPR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00416)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
A synthetic peptide of human SPR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with eNOS or nNOS.
Reactive Species
A00416 is reactive to SPR in Human, Mouse, Rat
Applications
A00416 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
28.048kDa
Background of SPR
Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Kan-Tai Hsia, Development, Jan 2003; 130: 369.
Jim Selfridge, Nucleic Acids Res., Nov 2001; 29: 4541 - 4550.
Cha-Kyung Youn, Cancer Res., Jul 2004; 64: 4849 - 4857.
Teresa A. Motycka, J. Biol. Chem., Apr 2004; 279: 13634 - 13639.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
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Western blot analysis of extracts of various cells, using SPR antibody.
Protein Target Info & Infographic
Gene/Protein Information For SPR (Source: Uniprot.org, NCBI)
Gene Name
SPR
Full Name
Sepiapterin reductase
Weight
28.048kDa
Superfamily
sepiapterin reductase family
Alternative Names
EC 1.1.1.153; Gm10328; SDR38C1; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR SPR SDR38C1 sepiapterin reductase sepiapterin reductase|Sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)|sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)|short chain dehydrogenase/reductase family 38C, member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SPR, check out the SPR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SPR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Sepiapterin reductase SPR Antibody (A00416)
Hello CJ!
A00416 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Alterations in the endometrium of rats, rabbits, and?Macaca mulatta?that received an implantation of copper/low-density polyethylene nanocomposite
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Customer Reviews
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