Anti-SERPINC1 Monoclonal Antibody

Product Name

Anti-SERPINC1 Monoclonal Antibody

View all Serpin C1/Antithrombin-III Antibodies

SKU/Catalog Number

M00469

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-SERPINC1 Monoclonal Antibody catalog # M00469. Tested in WB, ICC/IF applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SERPINC1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00469)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

ACCA-19

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human SERPINC1 Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00469 is reactive to SERPINC1 in Human

Applications

M00469 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

24 kDa, 29 kDa

Calculated molecular weight

52.602kDa

Background of Serpin C1/Antithrombin-III

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ICC/IF 1:50-1:200

Validation Images & Assay Conditions

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Western blot analysis of SERPINC1 expression in human plasma lysate.

Gene/Protein Information For SERPINC1 (Source: Uniprot.org, NCBI)

Alternative Names

Antithrombin-III; AT3antithrombin-III; ATIII; ATIIIantithrombin III; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine-cysteine proteinase inhibitor clade C member 1; Serpin C1; serpin peptidase inhibitor, clade C (antithrombin), member 1 SERPINC1 AT3, AT3D, ATIII, ATIII-R2, ATIII-T1, ATIII-T2, THPH7 serpin family C member 1 antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|serpin peptidase inhibitor clade C member 1|serpin peptidase inhibitor, clade C (antithrombin), member 1

For more info on SERPINC1, check out the SERPINC1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SERPINC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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