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- Table of Contents
Antithrombin-III Antibodies
AND SERPINC1 ELISA kits, Antithrombin-III Proteins
Many biological assays use antibodies to detect Antithrombin-III, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Antithrombin-III in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Antithrombin-III antibodies...
Designing a Western blot for Antithrombin-III? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SERPINC1 Western Blot GuideSERPINC1 Infographic by Boster Bio
All SERPINC1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1393
96 wells/kit, with removable strips.
Cat # EK1393
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ1393
5 plates/kit
Cat # EZ1393
5 plates/kit
Human
ELISA
$499
Cat # FEK1393
96 wells/kit, with removable strips.
Cat # FEK1393
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00469-1
100 μg/vial
Cat # A00469-1
100 μg/vial
Human
$960
Cat # LS000462
20 µg, 100 µg
Cat # LS000462
20 µg, 100 µg
SERPINC1 Overview
Facts about Antithrombin-III.
Antithrombin-III (SERPINC1)
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, in addition to factors IXa, Xa and XIa.
Its inhibitory activity is greatly enhanced in the presence of heparin. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SERPINC1 |
| Uniprot: | P01008 |
| Entrez: | 462 |
Family
| Belongs to: |
|---|
| serpin family |
Alternative Names
Antithrombin-III; AT3antithrombin-III; ATIII; ATIIIantithrombin III; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine-cysteine proteinase inhibitor clade C member 1; Serpin C1; serpin peptidase inhibitor, clade C (antithrombin), member 1
Molecular Weight
Mass (kDA):
52.602 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q25.1 |
| Sequence: | 1; NC_000001.11 (173903519..173917378, complement) |
Tissue Specificity
Found in plasma.
Subcellular Localizations
Secreted, extracellular space.
Diseases
- Antithrombin Iii Deficiency
- Thrombosis
- Venous Thrombosis
- Deep Vein Thrombosis
- Pulmonary Embolism
- Thrombophilia
- Embolism
- Thromboembolism
- Malignant Neoplasms
- Venous Thromboembolism
- Cholangiocarcinoma
- Carcinoma
- Cerebrovascular Accident
Interacting Proteins
- FAM20C
Pathways
- Coagulation
- Secretion
- Glycosylation
- Cell Adhesion
- Blood Coagulation
- Inflammatory Response
- Translation
- Growth Hormone Secretion
- Regulation Of Coagulation
- Protein Folding
PTMs
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINC1
bosterbio.com/bosterbio-gene-info-cards/SERPINC1
References
PMID: 6298709 by Bock S.C., et al. Cloning and expression of the cDNA for human antithrombin III.
PMID: 6572945 by Chandra T., et al. Isolation and sequence characterization of a cDNA clone of human antithrombin III.