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Product Info Summary
| SKU: | M00611 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-SIRT6 Rabbit Monoclonal Antibody
SKU/Catalog Number
M00611
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-SIRT6 Rabbit Monoclonal Antibody catalog # M00611. Tested in WB application. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SIRT6 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00611)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
HBA-19
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human SIRT6
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00611 is reactive to Sirt6 in Human
Applications
M00611 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
32-42 kDa, 65 kDa, 75 kDa
Calculated molecular weight
36.92kDa
Background of Sirt6
Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:2000
Validation Images & Assay Conditions
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Western blot analysis of SIRT6 expression in Jurkat cell lysate.
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
Protein Target Info & Infographic
Gene/Protein Information For Sirt6 (Source: Uniprot.org, NCBI)
Gene Name
Sirt6
Full Name
NAD-dependent protein deacetylase sirtuin-6
Weight
36.92kDa
Superfamily
sirtuin family
Alternative Names
EC 3.5.1.-; NAD-dependent deacetylase sirtuin-6; SIR2L6sir2-related protein type 6; SIR2-like protein 6; sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae); sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6; sirtuin 6; sirtuin type 6 Sirt6|2810449N18Rik, AI043036, Sir2l6|sirtuin 6|NAD-dependent protein deacetylase sirtuin-6|NAD-dependent deacetylase sirtuin-6|SIR2-like protein 6|regulatory protein SIR2 homolog 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Sirt6, check out the Sirt6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Sirt6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SIRT6 Rabbit Monoclonal Antibody (M00611)
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No publications found for M00611
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Customer Reviews
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