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Product Info Summary
| SKU: | A01375-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-SLCO1B1 Antibody
SKU/Catalog Number
A01375-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLCO1B1 Antibody (Catalog # A01375-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
SLCO1B1 antibody can be stored at 4°C, stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLCO1B1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01375-1)
Host
Rabbit
Contents
SLCO1B1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
SLCO1B1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLCO1B1. The immunogen is located within the last 50 amino acids of SLCO1B1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SLCO1B1 antibody is human specific. At least four isoforms of SLCO1B1 are known to exist. This antibody is predicted to not cross-react with other SLCO1B proteins.
Reactive Species
A01375-1 is reactive to SLCO1B1 in Human
Applications
A01375-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
76.449kDa
Background of SLCO1B1
SLCO1B1 is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and may play an important role in the clearance of bile acids and organic anions from the liver (1,2). It contains one Kazal-like domain and belongs to the organo-anion transporter family (2,3). SLCO1B1 is highly expressed in liver and is localized to the basolateral hepatocyte membrane. It is responsible for the hepatic uptake of the liver-specific hydroxymethylglutaryl-CoA reductase inhibitor in mouse, rat and human (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLCO1B1 antibody can be used for detection of SLCO1B1 by Western blot at 1 - 2 μg/ml. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLCO1B1 in human liver tissue lysate with SLCO1B1 antibody at 1 μg/ml.
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Immunocytochemistry of SLCO1B1 in HepG2 cells with SLCO1B1 antibody at 2.5 μg/ml.
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Immunofluorescence of SLCO1B1 in human liver tissue with SLCO1B1 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SLCO1B1 (Source: Uniprot.org, NCBI)
Gene Name
SLCO1B1
Full Name
Solute carrier organic anion transporter family member 1B1
Weight
76.449kDa
Superfamily
organo anion transporter (TC 2.A.60) family
Alternative Names
HBLRR; LST1; LST-1; LST-2; LST3; LST-3TM13; OATP1B1; OATP1B3; OATP2; OATP8; OATP-8; OATPC; OATP-C; SLC21A6; SLC21A8; SLCO1B1 solute carrier organic anion transporter family, member 1B1 SLCO1B1 HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family member 1B1 solute carrier organic anion transporter family member 1B1|OATP-2|liver-specific organic anion transporter 1|sodium-independent organic anion-transporting polypeptide 2|solute carrier family 21 (organic anion transporter), member 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLCO1B1, check out the SLCO1B1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLCO1B1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLCO1B1 Antibody (A01375-1)
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