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Product Info Summary
| SKU: | A07507 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLIT and NTRK-like protein 1 Slitrk1 Antibody
SKU/Catalog Number
A07507
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLIT and NTRK-like protein 1 Slitrk1 Antibody (Catalog # A07507). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Slitrk1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLIT and NTRK-like protein 1 Slitrk1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07507)
Host
Rabbit
Contents
Slitrk1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Slitrk1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Slitrk1. The immunogen is located within amino acids 630 - 680 of Slitrk1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Reactive Species
A07507 is reactive to Slitrk1 in Human, Mouse, Rat
Applications
A07507 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
77.817kDa
Background of Slitrk1
SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Slitrk1 antibody can be used for detection of Slitrk1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Slitrk1 in human brain tissue lysate with Slitrk1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of Slitrk1 in human brain tissue with Slitrk1 antibody at 2.5 μg/mL.
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Immunofluorescence of slitrk1 in human brain tissue with slitrk1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Slitrk1 (Source: Uniprot.org, NCBI)
Gene Name
Slitrk1
Full Name
SLIT and NTRK-like protein 1
Weight
77.817kDa
Superfamily
SLITRK family
Alternative Names
FLJ54428; KIAA1910KIAA0918; leucine rich repeat containing 12; Leucine-rich repeat-containing protein 12; LRRC12; RP11-395N17.1; SLIT and NTRK-like family, member 1; SLIT and NTRK-like protein 1; slit and trk like gene 1; SLITRK1; TTM Slitrk1|3200001I04Rik|SLIT and NTRK-like family, member 1|SLIT and NTRK-like protein 1|slit and trk like gene 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Slitrk1, check out the Slitrk1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Slitrk1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLIT and NTRK-like protein 1 Slitrk1 Antibody (A07507)
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