Anti-SOCS1 Antibody

SOCS-1 antibody

Boster Bio Anti-SOCS1 Antibody catalog # PA1074. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 3 publication(s).

Product Info Summary

SKU: PA1074
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-SOCS1 Antibody

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SKU/Catalog Number



100 μg/vial




Boster Bio Anti-SOCS1 Antibody catalog # PA1074. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SOCS1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1074)




Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.




Rabbit IgG


A synthetic peptide corresponding to a sequence at the C-terminus of human SOCS1 (197-211aa NPVLRDYLSSFPFQI), identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1074 is reactive to SOCS1 in Human, Mouse, Rat


PA1074 is guaranteed for IHC, WB Boster Guarantee

Background of SOCS-1

Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For SOCS1 (Source:, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Suppressor of cytokine signaling 1




SOCS1 family

Alternative Names

CIS1; Cish1; JAB; JABTec-interacting protein 3; JAK binding protein; JAK-binding protein; SOCS1; SOCS-1; SOCS-1CIS1; SSI-1; SSI-1CISH1; SSI1cytokine-inducible SH2 protein 1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; suppressor of cytokine signaling 1; TIP3; TIP-3; TIP3Cish1 SOCS1 CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP-3, TIP3 suppressor of cytokine signaling 1 suppressor of cytokine signaling 1|JAK binding protein|STAT induced SH3 protein 1|STAT-induced STAT inhibitor 1|Tec-interacting protein 3|cytokine-inducible SH2 protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SOCS1, check out the SOCS1 Infographic

SOCS1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SOCS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

PA1074 has been cited in 3 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo

The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small cell lung cancer cells

Yang M, Tian M, Zhang X, Xu J, Yang B, Yu J, Li F, Li Y, Li S, Li X. Oncotarget. 2017 Jun 16;8(57):96958-96969. doi: 10.18632/oncotarget.18555. eCollection 2017 Nov 14. Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabete...

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6 Customer Q&As for Anti-SOCS1 Antibody


Is there a BSA free version of anti-SOCS1 antibody PA1074 available?

Verified Customer

Verified customer

Asked: 2020-04-09


Thank you for your recent telephone inquiry. I can confirm that some lots of this anti-SOCS1 antibody PA1074 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2020-04-09


We are currently using anti-SOCS1 antibody PA1074 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2019-11-13


The anti-SOCS1 antibody (PA1074) has not been tested for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-11-13


I appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for t-cell lymphoma using anti-SOCS1 antibody PA1074. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2019-10-14


Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-10-14


Is a blocking peptide available for product anti-SOCS1 antibody (PA1074)?

Verified Customer

Verified customer

Asked: 2019-06-18


We do provide the blocking peptide for product anti-SOCS1 antibody (PA1074). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-06-18


I see that the anti-SOCS1 antibody PA1074 works with IHC, what is the protocol used to produce the result images on the product page?

N. Carter

Verified customer

Asked: 2018-10-17


You can find protocols for IHC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2018-10-17


My question regards to test anti-SOCS1 antibody PA1074 on rat t-cell lymphoma for research purposes, then I may be interested in using anti-SOCS1 antibody PA1074 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-06-06


The products we sell, including anti-SOCS1 antibody PA1074, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-06-06



Total: $315


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