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Product Info Summary
| SKU: | A06654 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-SPPL2A Antibody
SKU/Catalog Number
A06654
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SPPL2A Antibody catalog # A06654. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SPPL2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06654)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human VTI1A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A06654 is reactive to Sppl2a in Human, Mouse, Rat
Applications
A06654 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
58.129kDa
Background of Sppl2a
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. UniProtKB O89116
Ota T., Nat. Genet. 36:40-45(2004).
Deloukas P., Nature 429:375-381(2004).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000-1:5000
IHC: 1:50-1:200
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-SPPL2A Antibody A06654
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For Sppl2a (Source: Uniprot.org, NCBI)
Gene Name
Sppl2a
Full Name
Signal peptide peptidase-like 2A
Weight
58.129kDa
Superfamily
peptidase A22B family
Alternative Names
EC 3.4.23; EC 3.4.23.-; IMP-3; IMP3intramembrane cleaving protease; Intramembrane protease 3; Presenilin-like protein 2; PSL2; signal peptide peptidase-like 2A; SPPL2a; SPP-like 2A Sppl2a|2010106G01Rik, C130089K23Rik|signal peptide peptidase like 2A|signal peptide peptidase-like 2A|IMP-3|SPP-like 2A protein|intramembrane protease 3|presenilin-like protein 2|protein SPPL2a
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Sppl2a, check out the Sppl2a Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Sppl2a: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SPPL2A Antibody (A06654)
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No publications found for A06654
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Customer Reviews
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