Anti-Teashirt homolog 3 TSHZ3 Antibody

Product Name

Anti-Teashirt homolog 3 TSHZ3 Antibody

View all TSHZ3 Antibodies

SKU/Catalog Number

A08453

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Teashirt homolog 3 TSHZ3 Antibody (Catalog # A08453). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TSHZ3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Teashirt homolog 3 TSHZ3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08453)

Host

Rabbit

Contents

TSHZ3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

TSHZ3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TSHZ3. The immunogen is located within amino acids 60 - 110 of TSHZ3.

Reactive Species

A08453 is reactive to TSHZ3 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

118.6 kDa

Background of TSHZ3

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08453 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TSHZ3 antibody can be used for detection of TSHZ3 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information TSHZ3

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