Anti-TFPI Antibody

TFPI antibody

Boster Bio Anti-TFPI Antibody (Catalog # A01052-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01052-1
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-TFPI Antibody

View all TFPI Antibodies

SKU/Catalog Number

A01052-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-TFPI Antibody (Catalog # A01052-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TFPI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-TFPI Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01052-1)

Host

Rabbit

Contents

TFPI Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

TFPI antibody was raised against a 13 amino acid peptide near the amino terminus of human TFPI. The immunogen is located within amino acids 70 - 120 of TFPI.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.

Reactive Species

A01052-1 is reactive to TFPI in Human, Mouse, Rat

Applications

A01052-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

35.015kDa

Background of TFPI

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TFPI antibody can be used for detection of TFPI by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TFPI (Source: Uniprot.org, NCBI)

Gene Name

TFPI

Full Name

Tissue factor pathway inhibitor

Weight

35.015kDa

Alternative Names

convertin; EPI; EPITFPI1LACITFI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); tissue factor pathway inhibitor TFPI EPI, LACI, TFI1, TFPI tissue factor pathway inhibitor tissue factor pathway inhibitor|anti-convertin|extrinsic pathway inhibitor|tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TFPI, check out the TFPI Infographic

TFPI infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TFPI: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01052-1-0.1 mg

0.1 mg

$449

Free Secondary Antibody

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A01052-1
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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