Anti-TLR4 (S441) Antibody

TLR4 antibody

Boster Bio Anti-TLR4 (S441) Antibody catalog # A00017S441. Tested in WB,IHC,IF,IP applications. This antibody reacts with Human,Mouse,Rat. Cited in 4 publication(s).

Product Info Summary

SKU: A00017S441
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IP, IF, IHC, WB

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Product Name

Anti-TLR4 (S441) Antibody

View all TLR4 Antibodies

SKU/Catalog Number

A00017S441

Size

100ul

Form

Liquid

Description

Boster Bio Anti-TLR4 (S441) Antibody catalog # A00017S441. Tested in WB,IHC,IF,IP applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TLR4 (S441) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00017S441)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Clone Number

PI9-17

Isotype

IgG

Immunogen

Synthesized peptide derived from human p16 around the phosphorylation site of S326.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Weakly cross-reacts with dog p53.

Reactive Species

A00017S441 is reactive to TLR4 in Human, Mouse, Rat

Applications

A00017S441 is guaranteed for IP, IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

95.68kDa

Background of TLR4

Anti-Glycogen Synthase 1 pS641 antibody is validated by IHC, Western Blot and ELISA. Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephosphorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3 that mainly functions to phosphorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at S641. Phosphorylation of GS at S641 has been associated with Antiphospholipid Antibody Syndrome.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:100-1:200
IF: 1:50-1:200
IP: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For TLR4 (Source: Uniprot.org, NCBI)

Gene Name

TLR4

Full Name

Toll-like receptor 4

Weight

95.68kDa

Superfamily

Toll-like receptor family

Alternative Names

76B357.1; ARMD10; CD284 antigen; CD284; hTollhomolog of Drosophila toll; tlr4 76B357.1; TLR4 facs; TLR4 flow cytometry; TLR4 human; TLR4 ihc; TLR4 western blot; TLR4; TOLL; toll-like receptor 4 TLR4 ARMD10, CD284, TLR-4, TOLL toll like receptor 4 toll-like receptor 4|hToll|homolog of Drosophila toll|toll like receptor 4 protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TLR4, check out the TLR4 Infographic

TLR4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TLR4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00017S441 has been cited in 4 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Tetramethylpyrazine attenuates endotoxin-induced retinal inflammation by inhibiting microglial activation via the TLR4/NF-κB signalling pathway

Authors: Han X,Chen X,Chen S,Luo Q,Liu X,He A,He S,Qiu J,Chen P,Wu Y,Zhuang J,Yang M,Wu C,Wu N,Yang Y,Ge J,Zhuang J,Yu K.


Species: Rat
A00017S441 usage in article: APP:WB, SAMPLE:RETINAL TISSUE, DILUTION:1:200

Shi Y,Vistro WA,Bai X,Wu R,Chen C,Huang Y,Fazlani SA,Tarique I,Yang P,Chen Q.Effect of seasonal variance on intestinal epithelial barriers and the associated innate immune response of the small intestine of the Chinese soft-shelled turtles.Fish Shellfish
Species: Turtles
A00017S441 usage in article: APP:WB, SAMPLE:SMALL INTESTINE, DILUTION:1:75

Feng S,Ju L,Shao Z,Grzanna M,Jia L,Liu M.Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis.J Inflamm Res.2020 Jul 21;13:343-356.doi:10.2147/JIR.S254717.PMID: 32801828;PMCID:PMC7398876.
Species: Mouse
A00017S441 usage in article: APP:WB, SAMPLE:SPLEEN, DILUTION:NA

Bone marrow stromal cells improved functional recovery in spinal cord injury rats partly via the Toll‑like receptor‑4/nuclear factor‑κB signaling pathway Shi Bai, Hao Zhou, and Lijuan Wu Exp Ther Med. 2019 Jan; 17(1): 444–448. Published online 2018 Oct

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Order DetailsPrice
A00017S441-100ul

100ul

$405

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