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Product Info Summary
| SKU: | A00429 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Toll-like receptor 1 TLR1 Antibody
SKU/Catalog Number
A00429
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Toll-like receptor 1 TLR1 Antibody (Catalog # A00429). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
TLR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Toll-like receptor 1 TLR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00429)
Host
Rabbit
Contents
TLR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLR1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TLR1. The immunogen is located within amino acids 160 - 210 of TLR1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.
Reactive Species
A00429 is reactive to TLR1 in Human, Mouse
Applications
A00429 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
90.291kDa
Background of TLR1
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLR1 antibody can be used for detection of TLR1 by Western blot at 1 to 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLR1 in mouse spleen lysate with TLR1 antibody at (A) 1
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Immunohistochemistry of TLR1 in mouse spleen tissue with TLR1 antibody at 10 μg/mL.
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Immunofluorescence of TLR1 in Mouse Spleen tissue
Protein Target Info & Infographic
Gene/Protein Information For TLR1 (Source: Uniprot.org, NCBI)
Gene Name
TLR1
Full Name
Toll-like receptor 1
Weight
90.291kDa
Superfamily
Toll-like receptor family
Alternative Names
CD281 antigen; CD281; DKFZp547I0610; DKFZp564I0682; KIAA0012MGC126311; MGC104956; MGC126312; rsc786; TIL; TIL. LPRS5; TLR1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1 TLR1 CD281, TIL, TIL. LPRS5, rsc786 toll like receptor 1 toll-like receptor 1|toll/interleukin-1 receptor-like protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TLR1, check out the TLR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Toll-like receptor 1 TLR1 Antibody (A00429)
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No publications found for A00429
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