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Product Info Summary
| SKU: | A01914 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-Toll-like receptor 6 TLR6 Antibody
SKU/Catalog Number
A01914
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Toll-like receptor 6 TLR6 Antibody (Catalog # A01914). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse.
Storage & Handling
TLR6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Toll-like receptor 6 TLR6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01914)
Host
Rabbit
Contents
TLR6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6. The immunogen is located within amino acids 160 - 210 of TLR6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This TLR6 antibody is predicted to have no cross-reactivity to other members of the TLR protein family.
Reactive Species
A01914 is reactive to TLR6 in Human, Mouse
Applications
A01914 is guaranteed for ELISA, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
91.88kDa
Background of TLR6
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLR6 antibody can be used for detection of TLR6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLR6 in Daudi cell lysate with TLR6 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of TLR6 in Jurkat cells with TLR6 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TLR6 (Source: Uniprot.org, NCBI)
Gene Name
TLR6
Full Name
Toll-like receptor 6
Weight
91.88kDa
Superfamily
Toll-like receptor family
Alternative Names
CD286 antigen; CD286; TLR6; toll-like receptor 6 TLR6 CD286 toll like receptor 6 toll-like receptor 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TLR6, check out the TLR6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLR6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Toll-like receptor 6 TLR6 Antibody (A01914)
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No publications found for A01914
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Customer Reviews
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