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Product Info Summary
| SKU: | A04966-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 107 TMEM107 Antibody
SKU/Catalog Number
A04966-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 107 TMEM107 Antibody (Catalog # A04966-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Transmembrane protein 107 TMEM107 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04966-1)
Host
Rabbit
Contents
TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. The immunogen is located within amino acids 20 - 70 of TMEM107 .
Cross-reactivity
TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
Reactive Species
A04966-1 is reactive to TMEM107 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
15.5 kDa
Background of TMEM107
Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04966-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of TMEM107 in human lymph node tissue with TMEM107 antibody at 5 μg/mL.
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Immunofluorescence of TMEM107 in human lymph node tissue with TMEM107 antibody at 20 μg/mL.
Specific Publications For Anti-Transmembrane protein 107 TMEM107 Antibody (A04966-1)
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