Transmembrane protein 107 (Tmem107)

Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern intermediate and intermediate neuronal cell types.

During ciliogenesis modulates the ciliary transition zone localization of some MKS complicated proteins (PubMed:26595381, PubMed:26518474). .