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Product Info Summary
| SKU: | A01213 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Type-1 angiotensin II receptor AGTR1 Antibody
SKU/Catalog Number
A01213
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Type-1 angiotensin II receptor AGTR1 Antibody (Catalog # A01213). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
AGTR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Type-1 angiotensin II receptor AGTR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01213)
Host
Rabbit
Contents
AGTR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
AGTR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
P2RX7 antibody is human, mouse, and rat reactive. Multiple isoforms of P2RX7 are known to exist.
Reactive Species
A01213 is reactive to AGTR1 in Human, Mouse, Rat
Applications
A01213 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
41.061kDa
Background of AGTR-1
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/mL.
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Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 μg/mL.
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Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For AGTR1 (Source: Uniprot.org, NCBI)
Gene Name
AGTR1
Full Name
Type-1 angiotensin II receptor
Weight
41.061kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
AG2S; AGTR1; AGTR-1; AGTR1AAngiotensin II type-1 receptor; Angiostensin Receptor; angiotensin II receptor, type 1; angiotensin receptor 1; angiotensin receptor 1B; AT1; AT1AR; AT1AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1AGTR1B; AT2R1BAT1BR; HAT1R; type-1 angiotensin II receptor; type-1B angiotensin II receptor AGTR1 AG2SB, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R, AGTR1 angiotensin II receptor type 1 type-1 angiotensin II receptor|type-1B angiotensin II receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AGTR1, check out the AGTR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AGTR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Type-1 angiotensin II receptor AGTR1 Antibody (A01213)
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No publications found for A01213
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Customer Reviews
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