Product Info Summary
| SKU: | A06292 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-Zinc finger protein 521 ZNF521 Antibody
SKU/Catalog Number
A06292
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Zinc finger protein 521 ZNF521 Antibody (Catalog # A06292). Tested in ELISA, IHC-P applications. This antibody reacts with Human.
Storage & Handling
ZNF521 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Zinc finger protein 521 ZNF521 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06292)
Host
Rabbit
Contents
ZNF521 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZNF521 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ZNF521. The immunogen is located within amino acids 1160 - 1210 of ZNF521.
Cross-reactivity
ZNF521 antibody is human specific.
Reactive Species
A06292 is reactive to ZNF521 in Human
Observed Molecular Weight
68 kDa
Calculated molecular weight
147.9 kDa
Background of ZNF521
The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06292 is guaranteed for ELISA, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZNF521 antibody can be used for detection of ZNF521 by immunohistochemistry at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry of ZNF521 in human kidney tissue with ZNF521 antibody at 5 μg/mL.
Specific Publications For Anti-Zinc finger protein 521 ZNF521 Antibody (A06292)
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