Anti-Zinc transporter 8 SLC30A8 Antibody

Product Name

Anti-Zinc transporter 8 SLC30A8 Antibody

View all SLC30A8 Antibodies

SKU/Catalog Number

A01310

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Zinc transporter 8 SLC30A8 Antibody (Catalog # A01310). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Storage & Handling

SLC30A8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Zinc transporter 8 SLC30A8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01310)

Host

Rabbit

Contents

SLC30A8 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

SLC30A8 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human SLC30A8.

Cross-reactivity

Two isoforms of SLC30A8 are known to exist; this antibody will detect both isoforms. This SLC30A8 antibody is predicted to not cross-react with other members of the SLC30 protein family.

Reactive Species

A01310 is reactive to SLC30A8 in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

40.8 kDa

Background of SLC30A8

SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells (1). Allelic variants of SLC30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes (2), but no genetic association has been found with Type 1 diabetes (3). SLC30A8 expression in -cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01310 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SLC30A8 antibody can be used for Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information SLC30A8

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