ABR Antibodies

Active breakpoint cluster region-related protein (ABR)

GTPase-activating protein for RAC and CDC42.

Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.

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Gene Information

Human
Gene Name:	ABR
Uniprot:	Q12979
Entrez:	29

Family

Belongs to:
No superfamily

Alternative Names

active BCR-related gene; active breakpoint cluster region-related protein; FLJ45954; MDB

Molecular Weight

Mass (kDA):
97.598 kDA

Genomic Context

Human
Location:	17p13.3
Sequence:	17; NC_000017.11 (1003519..1229722, complement)

Tissue Specificity

Highly enriched in the brain. Much weaker expression in heart, lung and muscle.

Subcellular Localizations

Cell projection, dendritic spine. Cell projection, axon. Cell junction, synapse.

Diseases

• Sensorineural Hearing Loss (disorder)
• Hearing Problem
• Complete Hearing Loss
• Acoustic Neuroma
• Neoplasms
• Noise-induced Hearing Loss
• Nervousness
• Lymphoma, Non-hodgkin
• Conductive Hearing Loss
• Neuroma
• Presbycusis
• Auditory Neuropathy

• Otitis Media
• Neurilemmoma
• Hearing Loss, High-frequency
• Vertigo
• Ear Inflammation
• Hearing Loss, Bilateral

Pathways

• Reflex
• Aging
• Pathogenesis
• Localization
• Cell Death
• Transport
• Startle Response
• Myelination
• Regeneration
• Prepulse Inhibition
• Synaptic Transmission
• Secretion
• Coagulation

• Innervation
• Pigmentation
• Sulfate Reduction
• Lactation
• Brain Development
• Exocytosis
• Echolocation

PTMs

• Phosphorylation
• Reduction
• Cleavage
• Nitration
• Glycosylation

• Oxidation
• Methylation
• Sulphation
• Hydroxylation
• Amidation

Research Areas

• Angiogenesis
• Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABR

Best Uses Of The ABR Marker

Boster bio is a great source for high-affinity prima antibodies. It offers a wide array of antibodies with validated performance in immunohistochemistry, Western Blotting, and ELISA. Read on to learn more about the company, Boster bio, and their antibody product line. The ABR markers are a versatile tool to detect biomarkers within different samples.

Topics: Cochleas (cochleas)

The best use of the ABR marker is to identify the regions of the cochlea that represent speech. This method allows researchers to identify abnormalities in the inner ear. These findings are vital because they can be used by physicians and other professionals to improve patient care. In addition, the ABR marker is an excellent choice for genetic testing in patients with hearing loss. Numerous studies have shown a link between hearing loss and a decrease in inner-ear blood flow.

Topics: High-affinity prim antibodies

Boster Bio stocks over 16,000 different primary antibodies. Boster Bio offers a range of antibodies that include WB reagents, validated ELISA reagents, and more. They also make rabbit polyclonal antibody. The company also offers a secondary antibody that comes free with primary antibodies. The company produces all its antibodies in-house. They also use strict monitoring to ensure that they are biologically active.

Boster offers a broad range of custom services, in addition to their high-affinity prima antibodies. For instance, if you're looking to run an immunoassay in your lab, they offer troubleshooting handbooks to help you get it right the first time. Boster has been in business over 25 years and offers delivery to laboratories around the world. Bosterbio has more information.

High-affinity primary antibodies can also be used to perform experiments that require dual labeling. This allows researchers to ask more questions of their specimens and gain more contextual data. Moreover, secondary antibodies are highly useful for a variety of purposes, including immunohistochemistry, histopathology, and proteomics. Secondary antibodies can be used to count specific cell types. Secondary antibodies can also be used to supplement data.

Primary antibodies are produced in the host's own immune system. The building blocks of these antibodies are known as complementarity-determining regions. For more information, visit this page. Scientists immunize hosts with the antigen they wish for their research to create polyclonal primaries antibodies. Then, they collect antibodies from the host's eggs or serum. High quality primary antibodies are able to perform well in immunoassays.

Product: High-affinity primary antibodies

Boster Bio stocks primary antibodies for ELISA or IHC. They have been approved for use with ELISA, Flow Cytometry, ELISA and ELISA. They are also manufactured in-house so they retain biological activity and high quality standards. Boster Bio has everything you need, whether you are looking for a new or replacement antibody to start your laboratory.

Look at the Boster catalogue to find the right antibody for your project. These high-affinity prim antibodies have been extensively referenced in scientific journals for more 25 years. Boster Bio's Anti-KHDRBS2 antibody, catalog # A09665, has been tested in IP and IHC. It reacts with Human. It is also available as a 100-ul liquid.

Boster Bio High affinity primary antibodies are able to double-label specimens, allowing researchers to get richer contextual data. This unique feature allows you to identify multiple species from one specimen. It also makes it easy to identify specific species. This is especially useful if you're working with multiple samples or need to identify several cell types at a time.

High affinity antibodies are a great feature for immunologists. However, it is not always a good thing. It can be difficult to purify high affinity antibodies. Additionally, their affinity may hinder the process of elution. Sometimes, you might need to use more aggressive methods such as denaturing to remove the antibody from a sample. If this happens, you will end up with an antibody that doesn't have the specificity you need.