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- Table of Contents
ABR Antibodies
AND ABR ELISA kits, ABR Proteins
Many biological assays use antibodies to detect ABR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABR antibodies...
Designing a Western blot for ABR? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ABR Western Blot GuideABR Infographic by Boster Bio
All ABR Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01719
100 μg/vial
Cat # A01719
100 μg/vial
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M32338-1
100 μl/vial
Cat # M32338-1
100 μl/vial
Human
Flow Cytometry, IP, IHC-F, ICC, WB
$308
Cat # M33909
0.1 mg
Cat # M33909
0.1 mg
Human
Flow Cytometry, IP, WB
$330
Cat # M32338
0.1 mg
Cat # M32338
0.1 mg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00468-4
100 μg
Cat # M00468-4
100 μg
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00077-7
100 μg
Cat # M00077-7
100 μg
All species, E. coli
ICC, WB
$308
Cat # M33937
0.1 mg
Cat # M33937
0.1 mg
ABR Overview
Facts about Active breakpoint cluster region-related protein.
Active breakpoint cluster region-related protein (ABR)
GTPase-activating protein for RAC and CDC42.
Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them..
Gene Information
| Human | |
|---|---|
| Gene Name: | ABR |
| Uniprot: | Q12979 |
| Entrez: | 29 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
active BCR-related gene; active breakpoint cluster region-related protein; FLJ45954; MDB
Molecular Weight
Mass (kDA):
97.598 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.3 |
| Sequence: | 17; NC_000017.11 (1003519..1229722, complement) |
Tissue Specificity
Highly enriched in the brain. Much weaker expression in heart, lung and muscle.
Subcellular Localizations
Cell projection, dendritic spine. Cell projection, axon. Cell junction, synapse.
Diseases
- Sensorineural Hearing Loss (disorder)
- Hearing Problem
- Complete Hearing Loss
- Acoustic Neuroma
- Neoplasms
- Noise-induced Hearing Loss
- Nervousness
- Lymphoma, Non-hodgkin
- Conductive Hearing Loss
- Neuroma
- Presbycusis
- Auditory Neuropathy
Pathways
- Reflex
- Aging
- Pathogenesis
- Localization
- Cell Death
- Transport
- Startle Response
- Myelination
- Regeneration
- Prepulse Inhibition
- Synaptic Transmission
- Secretion
- Coagulation
PTMs
- Phosphorylation
- Reduction
- Cleavage
- Nitration
- Glycosylation
Research Areas
- Angiogenesis
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABR
bosterbio.com/bosterbio-gene-info-cards/ABR
References
PMID: 8262969 by Tan E.-C., et al. The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.
PMID: 8349582 by Heisterkamp N., et al. Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain.