ACADSB Antibodies

AND ACADSB ELISA kits, ACADSB Proteins

Many biological assays use antibodies to detect ACADSB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACADSB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACADSB antibodies...

We validate the specificity of these antibodies to ACADSB by testing them on tissues known to express ACADSB positively and negatively. Browse below to find the ACADSB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for ACADSB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ACADSB IHC Guide

ACADSB Infographic by Boster Bio

All ACADSB Products

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Product

Figures

Specificity

Applications

Price

Anti-SBCAD/ACADSB Antibody Picoband®

Western blot analysis of SBCAD/ACADSB using anti-SBCAD/ACADSB antibody (A08652-1)

IF analysis of SBCAD/ACADSB using anti-SBCAD/ACADSB antibody (A08652-1)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08652-1
100 μg/vial

ACADSB (NM_001609) Human Over-expression Lysate

Human

$628
Cat # LS000036
20 µg, 100 µg

Human ACADSB Recombinant Protein

SDS-PAGE

$275
Cat # PROTP45954
Starting from 10ug

ACADSB Overview

Facts about Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial.

ACADSB 3D structure. Source: alphafold

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB)

Has greatest action toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA in addition to toward short straight chain acyl-CoAs like butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of the agent.

Gene Information

Human
Gene Name:	ACADSB
Uniprot:	P45954
Entrez:	36

Family

Belongs to:

acyl-CoA dehydrogenase family

Alternative Names

2-MEBCAD; 2-methylbutyryl-coenzyme A dehydrogenase; ACAD7,2-methylbutyryl-CoA dehydrogenase; acyl-CoA dehydrogenase, short/branched chain; acyl-Coenzyme A dehydrogenase, short/branched chain; EC 1.3.99,2-methyl branched chain acyl-CoA dehydrogenase; EC 1.3.99.-; SBCADshort/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Molecular Weight

Mass (kDA):
47.485 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (123009006..123058317)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Dysequilibrium Syndrome
Cholangiocarcinoma
Sclerosis
Essential Hypertension
Multiple Sclerosis
Rickets
Diabetes Mellitus

Hypertensive Disease
Deficiency Of Acetyl-coa Acyltransferase (disorder)
Neoplasms, Hormone-dependent
Neoplasms

Pathways

Reverse Transcription
Pathogenesis
Localization
Excretion

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACADSB

References

PMID: 7698750 by Rozen R., et al. Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family.

PMID: 10832746 by Gibson K.M., et al. 2-methylbutyryl-coenzyme A dehydrogenase deficiency: a new inborn error of L-isoleucine metabolism.