Alkaline ceramidase 3 Antibodies

AND ACER3 ELISA kits, Alkaline ceramidase 3 Proteins

Many biological assays use antibodies to detect Alkaline ceramidase 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alkaline ceramidase 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alkaline ceramidase 3 antibodies...

We validate the specificity of these antibodies to Alkaline ceramidase 3 by testing them on tissues known to express ACER3 positively and negatively. Browse below to find the ACER3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Alkaline ceramidase 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ACER3 IHC Guide

ACER3 Infographic by Boster Bio

All ACER3 Products

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Anti-APHC ACER3 Antibody

Western Blot analysis of various cells using APHC Polyclonal Antibody

Western blot analysis of lysates from COLO cells, using PHCA Antibody

Western blot analysis of the lysates from HT-29 cells using PHCA antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A10457-2
100ul

PHCA Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$480
Cat # EKC1455
1 kit, containing one 96-well plate and all necessary reagents

ACER3 Overview

Facts about Alkaline ceramidase 3.

ACER3 3D structure. Source: alphafold

Alkaline ceramidase 3 (ACER3)

Hydrolyzes only phytoceramide to phytosphingosine and free fatty acid. Doesn't have reverse activity.

Gene Information

Human
Gene Name:	ACER3
Uniprot:	Q9NUN7
Entrez:	55331

Family

Belongs to:

alkaline ceramidase family

Alternative Names

Alkaline CDase 3; alkaline ceramidase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC; APHCAlkCDase 3; EC 3.5.1.-; FLJ11238; PHCA; phytoceramidase, alkaline

Molecular Weight

Mass (kDA):
31.552 kDA

Genomic Context


Human

Location:	11q13.5
Sequence:	11; NC_000011.10 (76860888..77026797)

Tissue Specificity

Ubiquitously expressed. Highest expression in placenta.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

Diseases

Malignant Squamous Cell Neoplasm
Skin Neoplasms
Tissue Adhesions
Farber Lipogranulomatosis

Pathways

Cell Proliferation
Cell Differentiation
Rna Interference

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACER3

References

PMID: 11356846 by Mao C., et al. Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.

PMID: 20207939 by Xu R., et al. Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.