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- Table of Contents
Acetylcholinesterase Antibodies
AND ACHE ELISA kits, Acetylcholinesterase Proteins
Many biological assays use antibodies to detect Acetylcholinesterase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acetylcholinesterase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acetylcholinesterase antibodies...
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ACHE Infographic by Boster Bio
All ACHE Products
Product
Figures
Specificity
Applications
Price
Anti-Acetylcholinesterase/ACHE Antibody Picoband®
3 Citations 15 Q&As
Human, Mouse, Rat
WB
$370
Cat # PB9417
100 μg/vial
Cat # PB9417
100 μg/vial
Human
ELISA
$750
Cat # EK2137
96 wells/kit, with removable strips.
Cat # EK2137
96 wells/kit, with removable strips.
Human
$628
Cat # LS000043
20 µg, 100 µg
Cat # LS000043
20 µg, 100 µg
ACHE Overview
Facts about Acetylcholinesterase.
Acetylcholinesterase (ACHE)
Terminates signal transduction in the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
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Gene Information
| Human | |
|---|---|
| Gene Name: | ACHE |
| Uniprot: | P22303 |
| Entrez: | 43 |
Family
| Belongs to: |
|---|
| type-B carboxylesterase/lipase family |
Alternative Names
acetylcholinesterase (Yt blood group); Acetylcholinesterase; ACHE; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1; EC 3.1.1.7; N-ACHE; Yt blood group; YT
Molecular Weight
Mass (kDA):
67.796 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (100889994..100896994, complement) |
Tissue Specificity
Isoform H is highly expressed in erythrocytes.
Subcellular Localizations
Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein.; [Isoform T]: Nucleus. Only observed in apoptotic nuclei.; [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Diseases
- Alzheimer's Disease
- Nervousness
- Poisoning
- Dementia
- Neurotoxicity Syndromes
- Pain
- Memory Impairment
- Malnutrition
- Headache
- Organophosphate Poisoning
- Stomach Ache
- Neurodegenerative Disorders
Interacting Proteins
- COLQ
- ENO1
- RACK1
Pathways
- Innervation
- Localization
- Aging
- Transport
- Secretion
- Pathogenesis
- Cognition
- Regeneration
- Cell Death
- Synaptic Transmission
- Swimming
- Insecticide Resistance
- Neuroprotection
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Glycosylation
- Acylation
- Phosphorothioation
- Carbamylation
- Phosphorothionation
- Biotinylation
Research Areas
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACHE
bosterbio.com/bosterbio-gene-info-cards/ACHE
References
PMID: 2263619 by Soreq H., et al. Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.
PMID: 8299725 by Karpel R., et al. Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins.