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- Table of Contents
Facts about Acetylcholinesterase.
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Human | |
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Gene Name: | ACHE |
Uniprot: | P22303 |
Entrez: | 43 |
Belongs to: |
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type-B carboxylesterase/lipase family |
acetylcholinesterase (Yt blood group); Acetylcholinesterase; ACHE; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1; EC 3.1.1.7; N-ACHE; Yt blood group; YT
Mass (kDA):
67.796 kDA
Human | |
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Location: | 7q22.1 |
Sequence: | 7; NC_000007.14 (100889994..100896994, complement) |
Isoform H is highly expressed in erythrocytes.
Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein.; [Isoform T]: Nucleus. Only observed in apoptotic nuclei.; [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
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To determine the maturation limits for affinity of these primary antibodies that are high-affinity, we conducted several tests. The 19-35 Abs affinity maturation limits were determined at physiological temperatures. Data were distributed across well-defined mean values. The temperature change did not affect the geometric mean of kon however it did increase the value of the koff by 2.4-fold that corresponded to a lower average interaction t1/2.
IgD plays an important function in controlling the release of antibodies in vivo. ISA.p>