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- Table of Contents
Acetylcholinesterase Antibodies
AND ACHE ELISA kits, Acetylcholinesterase Proteins
Many biological assays use antibodies to detect Acetylcholinesterase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acetylcholinesterase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acetylcholinesterase antibodies...
Designing a Western blot for Acetylcholinesterase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACHE Western Blot GuideACHE Infographic by Boster Bio
All ACHE Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9742
100 μg/vial
Cat # PB9742
100 μg/vial
Mouse
ELISA
$399
Cat # EK1150
96 wells/kit, with removable strips.
Cat # EK1150
96 wells/kit, with removable strips.
Human
$628
Cat # LS000043
20 µg, 100 µg
Cat # LS000043
20 µg, 100 µg
Enzyme Activity, SDS-PAGE
$300
Cat # PROTP22303-1
Starting from 10ug
Cat # PROTP22303-1
Starting from 10ug
ACHE Overview
Facts about Acetylcholinesterase.
Acetylcholinesterase (ACHE)
Terminates signal transduction in the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ACHE |
| Uniprot: | P22303 |
| Entrez: | 43 |
Family
| Belongs to: |
|---|
| type-B carboxylesterase/lipase family |
Alternative Names
acetylcholinesterase (Yt blood group); Acetylcholinesterase; ACHE; apoptosis-related acetylcholinesterase; ARACHE; EC 3.1.1; EC 3.1.1.7; N-ACHE; Yt blood group; YT
Molecular Weight
Mass (kDA):
67.796 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (100889994..100896994, complement) |
Tissue Specificity
Isoform H is highly expressed in erythrocytes.
Subcellular Localizations
Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein.; [Isoform T]: Nucleus. Only observed in apoptotic nuclei.; [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Diseases
- Alzheimer's Disease
- Nervousness
- Poisoning
- Dementia
- Neurotoxicity Syndromes
- Pain
- Memory Impairment
- Malnutrition
- Headache
- Organophosphate Poisoning
- Stomach Ache
- Neurodegenerative Disorders
Interacting Proteins
- COLQ
- ENO1
- RACK1
Pathways
- Innervation
- Localization
- Aging
- Transport
- Secretion
- Pathogenesis
- Cognition
- Regeneration
- Cell Death
- Synaptic Transmission
- Swimming
- Insecticide Resistance
- Neuroprotection
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Glycosylation
- Acylation
- Phosphorothioation
- Carbamylation
- Phosphorothionation
- Biotinylation
Research Areas
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACHE
bosterbio.com/bosterbio-gene-info-cards/ACHE
References
PMID: 2263619 by Soreq H., et al. Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.
PMID: 8299725 by Karpel R., et al. Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins.
2 Publications of Boster Acetylcholinesterase Antibodies & ELISA Kits
- PubMed ID: , Pretreatment tumor-related leukocytosis misleads positron emission tomography-co...
- PubMed ID: 32170086, Mabuchi S,Komura N,Sasano T,Shimura K,Yokoi E,Kozasa K,Kuroda H,Takahashi R,Kawa...
*More publications can be found for each product on its corresponding product page