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- Table of Contents
2 Citations 8 Q&As
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 1.
Cleaves aggrecan, a cartilage proteoglycan, in the'1938-Glu-
.| Human | |
|---|---|
| Gene Name: | ADAMTS1 |
| Uniprot: | Q9UHI8 |
| Entrez: | 9510 |

| Belongs to: |
|---|
| No superfamily |

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAMTS1; ADAM-TS1; ADAMTS-1; C3-C5; METH1; METH-1
Mass (kDA):
105.358 kDA

| Human | |
|---|---|
| Location: | 21q21.3 |
| Sequence: | 21; NC_000021.9 (26835755..26845409, complement) |
Secreted, extracellular space, extracellular matrix.




PMID: 10438512 by Vazquez F., et al. METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.
PMID: 10785405 by Glienke J., et al. Differential gene expression by endothelial cells in distinct angiogenic states.
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