Adenylate cyclase type 3 Antibodies

AND ADCY3 ELISA kits, Adenylate cyclase type 3 Proteins

Many biological assays use antibodies to detect Adenylate cyclase type 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenylate cyclase type 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenylate cyclase type 3 antibodies...

We validate the specificity of these antibodies to Adenylate cyclase type 3 by testing them on tissues known to express ADCY3 positively and negatively. Browse below to find the ADCY3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Adenylate cyclase type 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ADCY3 IHC Guide

ADCY3 Infographic by Boster Bio

All ADCY3 Products

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Anti-ADCY3 antibody

IHC analysis of ADCY3 using anti-ADCY3 antibody (A04795)

IF analysis of ADCY3 using anti-ADCY3 antibody (A04795)

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A04795
100 μl/vial

ADCY3 (NM_004036) Human Over-expression Lysate

Human

$960
Cat # LS000109
20 µg, 100 µg

ADCY3 Overview

Facts about Adenylate cyclase type 3.

ADCY3 3D structure. Source: alphafold

Adenylate cyclase type 3 (ADCY3)

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors through its function in cAMP biosynthesis.

Required for the perception of odorants. Required for normal sperm motility and normal male fertility.

Gene Information

Human
Gene Name:	ADCY3
Uniprot:	O60266
Entrez:	109

Family

Belongs to:

adenylyl cyclase class-4/guanylyl cyclase family

Alternative Names

AC3EC 4.6.1.1; AC-III; adenylate cyclase 3; adenylate cyclase type 3; Adenylate cyclase type III; Adenylyl cyclase 3; adenylyl cyclase, type III; ATP pyrophosphate-lyase 3; EC 4.6.1; KIAA0511; olfactive type

Molecular Weight

Mass (kDA):
128.96 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (24819169..24920237, complement)

Tissue Specificity

Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle (PubMed:9920776). Detected in testis (PubMed:15705663).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cytoplasm. Cell projection, cilium. Golgi apparatus. Also detected in the cytoplasm, close to lipid droplets.

Diseases

Liver Cirrhosis
Neoplasm Metastasis
Mood Disorders
Urinary Bladder Diseases
Infertility
Malignant Neoplasms
Nervousness
Osteoporosis
Bipolar Disorder
Dysequilibrium Syndrome
Male Infertility
Intraocular Pressure Disorder

Schizophrenia
Idiopathic Hypereosinophilic Syndrome
Diabetes Mellitus
Glaucoma
Female Infertility
Major Depressive Disorder

Pathways

Pathogenesis
Transport
Osteoclast Differentiation
Reverse Transcription
Sperm Motility
Ion Transport
Micturition
Oocyte Maturation

Bone Resorption
Meiosis

PTMs

Phosphorylation

Research Areas

Lipid and Metabolism
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCY3

References

PMID: 9920776 by Yang B., et al. Molecular cloning of a full-length cDNA for human type 3 adenylyl cyclase and its expression in human islets.

PMID: 8476432 by Hellevuo K., et al. A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.