This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Adenylate cyclase type 5.
Regulates the increase of free cytosolic Ca(2+) in response to increased blood sugar levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (PubMed:24740569). .
Human | |
---|---|
Gene Name: | ADCY5 |
Uniprot: | O95622 |
Entrez: | 111 |
Belongs to: |
---|
adenylyl cyclase class-4/guanylyl cyclase family |
AC5; adenylate cyclase 5; adenylate cyclase type 5; Adenylate cyclase type V; Adenylyl cyclase 5; ATP pyrophosphate-lyase 5; EC 4.6.1.1
Mass (kDA):
138.908 kDA
Human | |
---|---|
Location: | 3q21.1 |
Sequence: | 3; NC_000003.12 (123282296..123449090, complement) |
Detected in pancreas islets (at protein level). Detected in pancreas islets.
Cell membrane; Multi-pass membrane protein. Cell projection, cilium.
PMID: 12503609 by Ludwig M.G., et al. Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.
PMID: 10481931 by Raimundo S., et al. Cloning and sequence of partial cDNAs encoding the human type V and VI adenylyl cyclases and subsequent RNA-quantification in various tissues.