Adenylate cyclase type 5 Antibodies

AND ADCY5 ELISA kits, Adenylate cyclase type 5 Proteins

Many biological assays use antibodies to detect Adenylate cyclase type 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenylate cyclase type 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenylate cyclase type 5 antibodies...

We validate the specificity of these antibodies to Adenylate cyclase type 5 by testing them on tissues known to express ADCY5 positively and negatively. Browse below to find the ADCY5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: A1BG Next: ADCY6

ADCY5 Infographic by Boster Bio

All ADCY5 Products

Product

Figures

Specificity

Applications

Price

Anti-A Cyclase V/VI ADCY5 Antibody

13 Q&As

Human, Mouse, Rat

$399
Cat # A04197
100μl

Anti-ADCY 5/6 (F1052) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A04197-1
100ul

ADCY5 Overview

Facts about Adenylate cyclase type 5.

ADCY5 3D structure. Source: alphafold

Adenylate cyclase type 5 (ADCY5)

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542).

Regulates the increase of free cytosolic Ca(2+) in response to increased blood sugar levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (PubMed:24740569). .

Gene Information

Human
Gene Name:	ADCY5
Uniprot:	O95622
Entrez:	111

Family

Belongs to:

adenylyl cyclase class-4/guanylyl cyclase family

Alternative Names

AC5; adenylate cyclase 5; adenylate cyclase type 5; Adenylate cyclase type V; Adenylyl cyclase 5; ATP pyrophosphate-lyase 5; EC 4.6.1.1

Molecular Weight

Mass (kDA):
138.908 kDA

Genomic Context


Human

Location:	3q21.1
Sequence:	3; NC_000003.12 (123282296..123449090, complement)

Tissue Specificity

Detected in pancreas islets (at protein level). Detected in pancreas islets.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell projection, cilium.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Sensitivity
Insulin Resistance
Obesity
Leukemia
Lymphoid Leukemia
Prediabetes Syndrome
Myocardial Ischemia
Infarction
Cardiovascular Diseases
Myocardial Infarction
Dyskinetic Syndrome

Malignant Neoplasms
Myokymia
Nervousness
Asthma
Hyperglycemia
Philadelphia Chromosome
Chronic Lymphocytic Leukemia

Pathways

Insulin Secretion
Secretion
Glucose Homeostasis
Methylation
Dna Methylation
Cell Proliferation
Response To Metformin

Metaphase

PTMs

Methylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCY5

References

PMID: 12503609 by Ludwig M.G., et al. Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.

PMID: 10481931 by Raimundo S., et al. Cloning and sequence of partial cDNAs encoding the human type V and VI adenylyl cyclases and subsequent RNA-quantification in various tissues.