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- Table of Contents
Facts about Beta-2 adrenergic receptor.
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Human | |
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Gene Name: | ADRB2 |
Uniprot: | P07550 |
Entrez: | 154 |
Belongs to: |
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G-protein coupled receptor 1 family |
ADRB2; ADRB2R; ADRBR; adrenergic, beta-2-, receptor, surface; B2AR; B2ARADRB2R; BAR; beta-2 Adrenergic R; beta-2 adrenergic receptor; beta2 AdrenergicR; beta-2 AdrenergicR; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; BETA2AR; catecholamine receptor
Mass (kDA):
46.459 kDA
Human | |
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Location: | 5q32 |
Sequence: | 5; NC_000005.10 (148826611..148828623) |
Cell membrane; Multi-pass membrane protein. Early endosome. Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325).
PMID: 3026848 by Chung F.-Z., et al. Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors.
PMID: 3034889 by Kobilka B.K., et al. Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.