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- Table of Contents
ADRB2 Antibodies
AND ADRB2 ELISA kits, ADRB2 Proteins
Many biological assays use antibodies to detect ADRB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADRB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADRB2 antibodies...
Designing a Western blot for ADRB2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ADRB2 Western Blot GuideADRB2 Infographic by Boster Bio
All ADRB2 Products
Product
Figures
Specificity
Applications
Price
Human, Rat
WB
$370
Cat # PB9365
100 μg/vial
Cat # PB9365
100 μg/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M00072
100 μl
Cat # M00072
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1925
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1925
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$540
Cat # EKC2313
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2313
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2185
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2185
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$480
Cat # EKC1018
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1018
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS000154
20 µg, 100 µg
Cat # LS000154
20 µg, 100 µg
ADRB2 Overview
Facts about Beta-2 adrenergic receptor.
Beta-2 adrenergic receptor (ADRB2)
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ADRB2 |
| Uniprot: | P07550 |
| Entrez: | 154 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
ADRB2; ADRB2R; ADRBR; adrenergic, beta-2-, receptor, surface; B2AR; B2ARADRB2R; BAR; beta-2 Adrenergic R; beta-2 adrenergic receptor; beta2 AdrenergicR; beta-2 AdrenergicR; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; BETA2AR; catecholamine receptor
Molecular Weight
Mass (kDA):
46.459 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q32 |
| Sequence: | 5; NC_000005.10 (148826611..148828623) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Early endosome. Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325).
Diseases
- Asthma
- Hypertensive Disease
- Obesity
- Cardiovascular Diseases
- Heart Failure
- Diabetes Mellitus
- Chronic Obstructive Airway Disease
- Lung Diseases
- Essential Hypertension
- Malignant Neoplasms
- Dysequilibrium Syndrome
- Lung Diseases, Obstructive
- Nervousness
Interacting Proteins
- ADORA1
- ARRB2
- ARRDC3
- CNR1
- HNRNPK
- MAGI3
- MBP
- MGLL
- PRNP
- SLC9A3R1
Pathways
- Pathogenesis
- Aging
- Inflammatory Response
- Sensitization
- Transport
- Angiogenesis
- Translation
- Localization
- Glomerular Filtration
- Coagulation
- Bone Resorption
- Secretion
- Cell Adhesion
PTMs
- Oxidation
Research Areas
- Asthma
- GPCR
- Immunology
- Neuroscience
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADRB2
bosterbio.com/bosterbio-gene-info-cards/ADRB2
References
PMID: 3026848 by Chung F.-Z., et al. Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors.
PMID: 3034889 by Kobilka B.K., et al. Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.