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- Table of Contents
Facts about Anterior gradient protein 3.
.
Human | |
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Gene Name: | AGR3 |
Uniprot: | Q8TD06 |
Entrez: | 155465 |
Belongs to: |
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AGR family |
AG3; AG-3; AGR3; anterior gradient homolog 3 (Xenopus laevis); BCMP11; BCMP11AG3; Breast cancer membrane protein 11; hAG-3member 18; PDIA18
Mass (kDA):
19.171 kDA
Human | |
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Location: | 7p21.1 |
Sequence: | 7; NC_000007.14 (16854711..16881983, complement) |
Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668). Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690). Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690).
Endoplasmic reticulum. Found in the cytoplasm, which could include the endoplasmic reticulum.
PMID: 12477722 by Adam P.J., et al. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer.
PMID: 12592373 by Fletcher G.C., et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.