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- Table of Contents
AGR3 Antibodies
AND AGR3 ELISA kits, AGR3 Proteins
Many biological assays use antibodies to detect AGR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGR3 antibodies...
Designing an IHC experiment for AGR3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AGR3 IHC GuideAGR3 Infographic by Boster Bio
All AGR3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, IF, IHC, ICC
$335
Cat # A05950-1
100ul
Cat # A05950-1
100ul
AGR3 Overview
Facts about Anterior gradient protein 3.
Anterior gradient protein 3 (AGR3)
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | AGR3 |
| Uniprot: | Q8TD06 |
| Entrez: | 155465 |
Family
| Belongs to: |
|---|
| AGR family |
Alternative Names
AG3; AG-3; AGR3; anterior gradient homolog 3 (Xenopus laevis); BCMP11; BCMP11AG3; Breast cancer membrane protein 11; hAG-3member 18; PDIA18
Molecular Weight
Mass (kDA):
19.171 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p21.1 |
| Sequence: | 7; NC_000007.14 (16854711..16881983, complement) |
Tissue Specificity
Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668). Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690). Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690).
Subcellular Localizations
Endoplasmic reticulum. Found in the cytoplasm, which could include the endoplasmic reticulum.
Diseases
- Mrsa - Methicillin Resistant Staphylococcus Aureus Infection
- Infective Disorder
- Community-acquired Infections
- Staphylococcal Infections
- Pneumonia
- Abscess
- Soft Tissue Infections
- Pneumonia Necrotising
- Malignant Neoplasms
- Neoplasms
- Cross Infection
- Neoplasm Metastasis
- Malignant Neoplasm Of Ovary
Interacting Proteins
- ERLIN1
- NUP62
- SGTA
- SGTB
- UBQLN1
- UBQLN2
Pathways
- Virulence
- Regeneration
- Protein Folding
- Dedifferentiation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGR3
bosterbio.com/bosterbio-gene-info-cards/AGR3
References
PMID: 12477722 by Adam P.J., et al. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer.
PMID: 12592373 by Fletcher G.C., et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.