ALAS1 Antibodies

AND ALAS1 ELISA kits, ALAS1 Proteins

Many biological assays use antibodies to detect ALAS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALAS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALAS1 antibodies...

We validate the specificity of these antibodies to ALAS1 by testing them on tissues known to express ALAS1 positively and negatively. Browse below to find the ALAS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ALAS1 Infographic by Boster Bio

All ALAS1 Products

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Specificity

Applications

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Anti-Alas1/Alas H Rabbit Monoclonal Antibody

1 Q&As

Western blot analysis of Alas1 expression in HepG2 cell lysate

Human

IF, ICC, WB

$370
Cat # M10405
100 μl

Anti-Alas1 Antibody Picoband®

Western blot analysis of Alas1 using anti-Alas1 antibody (A10405-1)

Flow Cytometry analysis of HEL cells using anti-Alas1 antibody (A10405-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A10405-1
100 μg/vial

ALAS1 (NM_000688) Human Over-expression Lysate

ALAS1 Human Over-expression Lysates NM_000688

Human

$628
Cat # LS000211
20 µg, 100 µg

ALAS1 Overview

Facts about 5-aminolevulinate synthase, nonspecific, mitochondrial.

ALAS1 3D structure. Source: alphafold

5-aminolevulinate synthase, nonspecific, mitochondrial (ALAS1)

Gene Information

Human
Gene Name:	ALAS1
Uniprot:	P13196
Entrez:	211

Family

Belongs to:

class-II pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

5-aminolevulinic acid synthase 1; ALAS; ALAS3; ALASH; ALAS-H; aminolevulinate, delta-, synthase 1; Delta-ALA synthase 1,5-aminolevulinate synthase, nonspecific, mitochondrial; Delta-aminolevulinate synthase 1; EC 2.3.1; EC 2.3.1.37; MIG4; migration-inducing protein 4

Molecular Weight

Mass (kDA):
70.581 kDA

Genomic Context


Human

Location:	3p21.2
Sequence:	3; NC_000003.12 (52198083..52214327)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Disorders Of Porphyrin Metabolism
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Acute Intermittent Porphyria
Neoplasms
Sideroblastic Anemia
Porphyrias, Hepatic
Anemia
Hereditary Sideroblastic Anemia
Ataxia
Hypoxia
Carcinoma
Ovarian Neoplasm

Stresses, Oxidative
Liver Carcinoma
Inflammation
Malignant Neoplasm Of Ovary
Intraepithelial Neoplasia
Malignant Neoplasm Of Breast
Kidney Neoplasm

Interacting Proteins

BCL7A
C2orf42
CDC73
CERK
DUSP19

EP400
GNL3L
KLHL35
LONRF1
MTFR2

POLDIP2
PPL
RTL8B
SH2D4A
SNX20

TCEA2
TEKT4
TMSB10
TTC23
USP20

WIPF1
ZNF175
ZNF564

Pathways

Transport
Pathogenesis
Localization
Translation
Cell Differentiation
Oxygen Transport
Response To Carbon Monoxide
Skeletal Muscle Adaptation
Cellular Homeostasis
Proteolysis
Oxidative Phosphorylation
Muscle Adaptation
Biosynthetic Process

Reverse Transcription
Mitochondrial Transport
Angiogenesis
Fatty Acid Oxidation
Glucose Transport
Excretion
Chromatin Remodeling

PTMs

Phosphorylation
Hydroxylation

Cleavage
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALAS1

References

PMID: 2263504 by Bishop D.F.; Two different genes encode delta-aminolevulinate synthase in humans: nucleotide sequences of cDNAs for the housekeeping and erythroid genes.

PMID: 3671094 by Bawden M.J., et al. Sequence of human 5-aminolevulinate synthase cDNA.