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Has a dual activity since it also converts leukotriene A4/LTA4 into the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it modulates distinct biological processes including platelet activation.
|Sequence:||17; NC_000017.11 (6993791..7010754)|
Expressed in vascular smooth muscle cells.
Cytoplasm, cytosol. Membrane. Membrane association is stimulated by EGF.