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- Table of Contents
Angiomotin Antibodies
AND Amot ELISA kits, Angiomotin Proteins
Many biological assays use antibodies to detect Angiomotin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Angiomotin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Angiomotin antibodies...
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Amot Infographic by Boster Bio
All Amot Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, WB
$523
Cat # M04170-1
100 µl
Cat # M04170-1
100 µl
Human, Mouse, Rat
IHC, WB
$523
Cat # M04170
100 µl
Cat # M04170
100 µl
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04170-1
100 μg/vial
Cat # A04170-1
100 μg/vial
Amot Overview
Facts about Angiomotin.
Angiomotin (Amot)
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation.
May also play a role in the assembly of endothelial cell-cell junctions (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Amot |
| Uniprot: | Q8VHG2 |
| Entrez: | 27494 |
Family
| Belongs to: |
|---|
| angiomotin family |
Alternative Names
angiomotin p80 isoform; angiomotin; KIAA1071angiomotin p130 isoform
Molecular Weight
Mass (kDA):
120.915 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | X|X F2 |
| Sequence: | X; |
Tissue Specificity
Expressed in brain, skeletal muscle and placenta.
Diseases
- Tumor Angiogenesis
- Neoplasms
- Pathologic Neovascularization
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Cell Invasion
- Neoplasm Metastasis
- Carcinoma
- Cell Transformation, Neoplastic
- Hyperplasia
- Overlying Behavior
- Diabetic Nephropathy
Pathways
- Angiogenesis
- Cell Migration
- Localization
- Endothelial Cell Migration
- Cell Motility
- Tube Formation
- Gastrulation
- Cell Growth
- Contact Inhibition
- Endoderm Formation
- Sprouting Angiogenesis
- Cell Proliferation
- Gene Silencing
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Amot
bosterbio.com/bosterbio-gene-info-cards/Amot
References
PMID: 12406577 by Bratt A., et al. Angiomotin belongs to a novel protein family with conserved coiled- coil and PDZ binding domains.